Hey there, sciencemamas! Today, we're diving deep into a topic that affects many of us but often goes unspoken: Irritable Bowel Syndrome (IBS). Let's explore how nutrition can be a game-changer in managing this tricky condition.
IBS isn't just about an upset stomach. It's a complex gut-brain interaction disorder that affects about 4% of adults worldwide
If you've experienced:
Bloating that makes you look six months pregnant (when you're definitely not)
Cramping that seems to come out of nowhere
Unpredictable swings between rushing to the loo and not going for days
...you might be dealing with IBS. And let's be honest, as busy moms, we don't have time for that!
IBS is like a miscommunication between your gut and your brain. This can lead to:
Gut motility issues
Visceral hypersensitivity (your gut becomes extra sensitive)
Immune system activation
Changes in gut bacteria
Here's the good news: what you eat can make a big difference. More than half of people with IBS say their symptoms are triggered by certain foods
But before you start cutting out everything you love, let's talk about a smarter approach.
While many focus on avoiding trigger foods, we might be missing out on some tiny but mighty helpers: micronutrients. These vitamins and minerals are the unsung heroes of gut health. Let's meet some of these superheroes:
Zinc: More than Just a Immune Booster
We often hear about zinc when we’re feeling under the weather, but did you know it also plays a role in the health of your gut? Zinc helps maintain the structure of the intestinal barrier, acting like a shield that protects against harmful pathogens. It also plays a role in keeping the tight junctions in the gut intact, which is super important for preventing unwanted substances from entering the bloodstream. Plus, zinc may even help reduce the damage done by harmful gut bacteria by stressing their cell envelopes—pretty cool, right?
Calcium: The Dairy Problem
Calcium’s role is another big one. Many IBS sufferers avoid dairy because it can cause bloating or discomfort, especially if you’re sensitive to lactose. This is where the low FODMAP diet comes in, which suggests cutting out dairy for this reason. But did you know that calcium could actually play a role in your gut health? It helps maintain the gut lining, so it’s essential to find other sources of calcium if dairy is a no-go for you. Think leafy greens, fortified plant-based milks, and even some beans!
Magnesium: A Game Changer for Constipation
Magnesium is often overlooked, but it’s super important, especially when it comes to constipation, a common issue in IBS. Magnesium helps regulate stool consistency and promotes regular bowel movements. In fact, some studies suggest that magnesium oxide can be used as a first-line treatment for chronic constipation, and it might even reduce the strain that many IBS sufferers experience when going to the bathroom. In practice, many also find relief with another form of magnesium - magnesium citrate!
Vitamin B6: The Immune System Helper
Now, let’s talk about Vitamin B6 (also known as pyridoxine). This vitamin is known for its anti-inflammatory and antioxidant properties, which are key in managing IBS. B6 can actually help modulate the immune system in the gut, which is important since IBS often involves inflammation in the intestines. Plus, it can help change the way inflammation looks at a molecular level, which may improve gut function over time.
Importantly, vitamin B6 is FMN dependent (i.e. depends on sufficient levels of first active form of vitamin b2 in the body).
Folate (Vitamin B9): Gut Immunity and Health
Speaking of vitamins, Vitamin B9 (or folate) is another one to consider. In animal studies, folate was shown to help modulate the immune system in the gut, which could be really beneficial for those dealing with IBS-related inflammation. A lack of folate can actually reduce the number of immune-regulating cells in the small intestine, leading to more inflammation—definitely something we want to avoid!
Vitamin B12: A Gut-Supporting Powerhouse
And don’t forget about Vitamin B12. It’s known for its ability to help regulate the immune system and even support gut bacteria in maintaining a healthy balance. It may help keep the gut-friendly bacteria in check and play a role in reducing inflammation. However, there’s still some mixed evidence on whether B12 supplementation directly improves fatigue or quality of life in IBS patients—so while it’s helpful for overall gut health, it might not be a miracle worker on its own.
Important to note that functional status of vitamin B12 may depend on the sufficiency of active forms of vitamin B2!
Vitamin D: More Than Just Bone Health
Finally, let’s talk about Vitamin D. This vitamin isn’t just for bones—it’s also a big player when it comes to regulating the immune system and gut health. Studies have shown that Vitamin D supplementation can improve IBS symptoms and overall quality of life. In fact, research suggests it plays a role in electrolyte balance, which is essential for digestive function.
ScienceMama's Action Plan
Keep a food diary: Track what you eat and how it makes you feel. You might spot patterns you never noticed before.
Balance is key: If you're avoiding certain foods, make sure you're still getting those essential nutrients from other sources.
Consider supplements: Chat with your healthcare provider about whether you might benefit from supplements, especially vitamin D and B-complex vitamins.
Timing matters: Try to eat regular meals to help stabilise your gut's natural rhythm.
Don't go it alone: Working with a nutritionist or dietitian can be a game-changer in navigating dietary changes without risking deficiencies.
Remember, mamas, managing IBS isn't about depriving yourself. It's about nourishing your body with the right foods and addressing any nutrient deficiencies. By doing this, you're giving your gut (and yourself) the tools to thrive.
So, let's eat for nourishment for happy, healthy guts! Because when our guts are happy, we're better equipped to handle whatever motherhood throws our way.
What about you, fellow science mamas? Have you tried focusing on micronutrients to manage IBS? Share your experiences in the comments below – your story might just help another mama feel less alone on her gut health journey!
References
Abbasnezhad, A., Amani, R., Hasanvand, A., Yousefi Rad, E., Alipour, M., Saboori, S. and Choghakhori, R., 2019. Association of serum vitamin D concentration with clinical symptoms and quality of life in patients with irritable bowel syndrome. Journal of the American College of Nutrition, 38(4), pp.327-333.
Aranow, C., 2011. Vitamin D and the immune system. Journal of investigative medicine, 59(6), pp.881-886.
Barrett, J.S., 2017. How to institute the low‐FODMAP diet. Journal of gastroenterology and hepatology, 32, pp.8-10.Basu, T.K. and Donaldson, D., 2003. Intestinal absorption in health and disease: micronutrients. Best practice & research Clinical gastroenterology, 17(6), pp.957-979.
Bek, S., Teo, Y.N., Tan, X.H., Fan, K.H. and Siah, K.T.H., 2022. Association between irritable bowel syndrome and micronutrients: A systematic review. Journal of Gastroenterology and Hepatology, 37(8), pp.1485-1497.
Bell, T.D., Demay, M.B. and Burnett‐Bowie, S.A.M., 2010. The biology and pathology of vitamin D control in bone. Journal of cellular biochemistry, 111(1), pp.7-13.
Bellini, M., Tonarelli, S., Nagy, A.G., Pancetti, A., Costa, F., Ricchiuti, A., de Bortoli, N., Mosca, M., Marchi, S. and Rossi, A., 2020. Low FODMAP diet: evidence, doubts, and hopes. Nutrients, 12(1), p.148.
Bird, R.P., 2018. The emerging role of vitamin B6 in inflammation and carcinogenesis. Advances in food and nutrition research, 83, pp.151-194.
Böhn, L., Störsrud, S. and Simrén, M., 2013. Nutrient intake in patients with irritable bowel syndrome compared with the general population. Neurogastroenterology & motility, 25(1), pp.23-e1
Böhn, L., Störsrud, S., Törnblom, H., Bengtsson, U. and Simrén, M., 2013. Self-reported food-related gastrointestinal symptoms in IBS are common and associated with more severe symptoms and reduced quality of life. Official journal of the American College of Gastroenterology| ACG, 108(5), pp.634-641
Burns, G., Carroll, G., Mathe, A., Horvat, J., Foster, P., Walker, M.M., Talley, N.J. and Keely, S., 2019. Evidence for local and systemic immune activation in functional dyspepsia and the irritable bowel syndrome: a systematic review. Official journal of the American College of Gastroenterology| ACG, 114(3), pp.429-436.Canavan, C., West, J. and Card, T., 2014. The economic impact of the irritable bowel syndrome. Alimentary pharmacology & therapeutics, 40(9), pp.1023-1034.
Cho, Y., Lee, Y., Choi, Y. and Jeong, S., 2018. Association of the vitamin D level and quality of school life in adolescents with irritable bowel syndrome. Journal of clinical medicine, 7(12), p.500
Cordonnier, C., Le Bihan, G., Emond-Rheault, J.G., Garrivier, A., Harel, J. and Jubelin, G., 2016. Vitamin B12 uptake by the gut commensal bacteria Bacteroides thetaiotaomicron limits the production of shiga toxin by enterohemorrhagic Escherichia coli. Toxins, 8(1), p.14.Drossman, D.A. and Hasler, W.L., 2016. Rome IV—functional GI disorders: disorders of gut-brain interaction. Gastroenterology, 150(6), pp.1257-1261
Drossman, D.A., Camilleri, M., Mayer, E.A. and Whitehead, W.E., 2002. AGA technical review on irritable bowel syndrome. Gastroenterology, 123(6), pp.2108-2131
El Amrousy, D., Hassan, S., El Ashry, H., Yousef, M. and Hodeib, H., 2018. Vitamin D supplementation in adolescents with irritable bowel syndrome: Is it useful? A randomized controlled trial. Saudi Journal of Gastroenterology, 24(2), pp.109-114
Eswaran, S., Dolan, R.D., Ball, S.C., Jackson, K. and Chey, W., 2020. The impact of a 4-week low-FODMAP and mNICE diet on nutrient intake in a sample of US adults with irritable bowel syndrome with diarrhea. Journal of the Academy of Nutrition and Dietetics, 120(4), pp.641-649.
Friedman, P.A. and Gesek, F.A., 1995. Cellular calcium transport in renal epithelia: measurement, mechanisms, and regulation. Physiological reviews, 75(3), pp.429-471.Gombart, A.F., Pierre, A. and Maggini, S., 2020. A review of micronutrients and the immune system–working in harmony to reduce the risk of infection. Nutrients, 12(1), p.236.
Gralnek, I.M., Hays, R.D., Kilbourne, A., Naliboff, B. and Mayer, E.A., 2000. The impact of irritable bowel syndrome on health-related quality of life. Gastroenterology, 119(3), pp.654-660.
Guo, Y.B., Zhuang, K.M., Kuang, L., Zhan, Q., Wang, X.F. and Liu, S.D., 2015. Association between diet and lifestyle habits and irritable bowel syndrome: a case-control study. Gut and liver, 9(5), p.649.
Gwee, K.A., Ghoshal, U.C. and Chen, M., 2018. Irritable bowel syndrome in Asia: pathogenesis, natural history, epidemiology, and management. Journal of gastroenterology and hepatology, 33(1), pp.99-110.
Halpert, A., Dalton, C.B., Palsson, O., Morris, C., Hu, Y., Bangdiwala, S., Hankins, J., Norton, N. and Drossman, D., 2007. What patients know about irritable bowel syndrome (IBS) and what they would like to know. National Survey on Patient Educational Needs in IBS and development and validation of the Patient Educational Needs Questionnaire (PEQ). Official journal of the American College of Gastroenterology| ACG, 102(9), pp.1972-1982.
Hayes, P.A., Fraher, M.H. and Quigley, E.M., 2014. Irritable bowel syndrome: the role of food in pathogenesis and management. Gastroenterology & hepatology, 10(3), p.164.
Henderson, S.J., Xia, J., Wu, H., Stafford, A.R., Leslie, B.A., Fredenburgh, J.C., Weitz, D.A. and Weitz, J.I., 2016. Zinc promotes clot stability by accelerating clot formation and modifying fibrin structure. Thrombosis and haemostasis, 115(03), pp.533-542.
Ho, E.Y. and Mathy, C., 2014. Functional abdominal pain causing Scurvy, Pellagra, and Hypovitaminosis A. F1000Research, 3.
Holtmann, G.J., Ford, A.C. and Talley, N.J., 2016. Pathophysiology of irritable bowel syndrome. The lancet Gastroenterology & hepatology, 1(2), pp.133-146.Jalili, M., Hekmatdoost, A., Vahedi, H., Poustchi, H., Khademi, B., Saadi, M., Zemestani, M. and Janani, L., 2016. Co-Administration of soy isoflavones and Vitamin D in management of irritable bowel disease. PloS one, 11(8), p.e0158545.
Jalili, M., Vahedi, H., Poustchi, H. and Hekmatdoost, A., 2019. Effects of vitamin D supplementation in patients with irritable bowel syndrome: a randomized, double-blind, placebo-controlled clinical trial. International journal of preventive medicine, 10(1), p.16.
Khayyat, Y. and Attar, S., 2015. Vitamin D deficiency in patients with irritable bowel syndrome: does it exist?. Oman medical journal, 30(2), p.115.
Khayyatzadeh, S.S., Vatanparast, H., Avan, A., Bagherniya, M., Bahrami, A., Kiani, M.A., Bahrami-Taghanaki, H., Ferns, G.A. and Ghayour-Mobarhan, M., 2018. Serum transaminase concentrations and the presence of irritable bowel syndrome are associated with serum 25-hydroxy vitamin D concentrations in adolescent girls who are overweight and obese. Annals of Nutrition and Metabolism, 71(3-4), pp.234-241.
Kinoshita, M., Kayama, H., Kusu, T., Yamaguchi, T., Kunisawa, J., Kiyono, H., Sakaguchi, S. and Takeda, K., 2012. Dietary folic acid promotes survival of Foxp3+ regulatory T cells in the colon. The Journal of Immunology, 189(6), pp.2869-2878.
Koloski, N.A., Talley, N.J. and Boyce, P.M., 2000. The impact of functional gastrointestinal disorders on quality of life. Official journal of the American College of Gastroenterology| ACG, 95(1), pp.67-71.
Lacy, B.E., Pimentel, M., Brenner, D.M., Chey, W.D., Keefer, L.A., Long, M.D. and Moshiree, B., 2021. ACG clinical guideline: management of irritable bowel syndrome. Official journal of the American College of Gastroenterology| ACG, 116(1), pp.17-44.
Lea, R. and Whorwell, P.J., 2003. New insights into the psychosocial aspects of irritable bowel syndrome. Current gastroenterology reports, 5(4), pp.343-350.
Maggini, S., Pierre, A. and Calder, P.C., 2018. Immune function and micronutrient requirements change over the life course. Nutrients, 10(10), p.1531
McKenzie, Y.A., Bowyer, R.K., Leach, H., Gulia, P., Horobin, J., O'Sullivan, N.A., Pettitt, C., Reeves, L.B., Seamark, L., Williams, M. and Thompson, J., 2016. British Dietetic Association systematic review and evidence‐based practice guidelines for the dietary management of irritable bowel syndrome in adults (2016 update). Journal of Human Nutrition and Dietetics, 29(5), pp.549-575.
Mellies, J.L., Thomas, K., Turvey, M., Evans, N.R., Crane, J., Boedeker, E. and Benison, G.C., 2012. Zinc–induced envelope stress diminishes type III secretion in enteropathogenic Escherichia coli. BMC microbiology, 12, pp.1-10.
Miyoshi, Y., Tanabe, S. and Suzuki, T., 2016. Cellular zinc is required for intestinal epithelial barrier maintenance via the regulation of claudin-3 and occludin expression. American Journal of Physiology-Gastrointestinal and Liver Physiology, 311(1), pp.G105-G116.Moayyedi,
P., Simren, M. and Bercik, P., 2020. Evidence-based and mechanistic insights into exclusion diets for IBS. Nature Reviews Gastroenterology & Hepatology, 17(7), pp.406-413.
Mori, S., Tomita, T., Fujimura, K., Asano, H., Ogawa, T., Yamasaki, T., Kondo, T., Kono, T., Tozawa, K., Oshima, T. and Fukui, H., 2019. A randomized double-blind placebo-controlled trial on the effect of magnesium oxide in patients with chronic constipation. Journal of neurogastroenterology and motility, 25(4), p.563.
Nanayakkara, W.S., Skidmore, P.M., O'Brien, L., Wilkinson, T.J. and Gearry, R.B., 2016. Efficacy of the low FODMAP diet for treating irritable bowel syndrome: the evidence to date. Clinical and experimental gastroenterology, pp.131-142.
Nwosu, B.U., Maranda, L. and Candela, N., 2017. Vitamin D status in pediatric irritable bowel syndrome. PLoS One, 12(2), p.e0172183.
O'Brien, L., Skidmore, P., Wall, C., Wilkinson, T., Muir, J., Frampton, C. and Gearry, R., 2020. A low FODMAP diet is nutritionally adequate and therapeutically efficacious in community dwelling older adults with chronic diarrhoea. Nutrients, 12(10), p.3002.Pimentel, M. and Lembo, A., 2020. Microbiome and its role in irritable bowel syndrome. Digestive diseases and sciences, 65, pp.829-839.
Ryan-Harshman, M. and Aldoori, W., 2005. Health benefits of selected minerals. Canadian family physician, 51(5), p.673.Schoen, M.S., Lindenbaum, J., Roginsky, M.S. and Holt, P.R., 1978. Significance of serum level of 25-hydroxycholecalciferol in gastrointestinal disease. The American journal of digestive diseases, 23, pp.137-142.
Scholten, A.M., Vermeulen, E., Dhonukshe-Rutten, R.A., Verhagen, T., Visscher, A., Olivier, A., Timmer, L. and Witteman, B.J., 2018. Surplus vitamin B12 use does not reduce fatigue in patients with irritable bowel syndrome or inflammatory bowel disease: a randomized double-blind placebo-controlled trial. Clinical nutrition ESPEN, 23, pp.48-53.
Selhub, J., Byun, A., Liu, Z., Mason, J.B., Bronson, R.T. and Crott, J.W., 2013. Dietary vitamin B6 intake modulates colonic inflammation in the IL10−/− model of inflammatory bowel disease. The Journal of nutritional biochemistry, 24(12), pp.2138-2143.